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The nation will be watching Missouri Tuesday as it becomes the first state to put president Obama's health care bill to a popularity vote.

If passed, Proposition C would prohibit governments from requiring people to have health insurance.

A "no" vote will simple allow the federal healthcare bill to take effect and require you to buy the insurance.

Both sides of the Prop C debate are trying to get the vote out.

Republicans seem confident they'll win, and their opposition is already planning ahead.

If passed, Prop C will also modify laws regarding insurance companies and how they can liquidate assets to go out of business.

Missouri Republican Party Executive Director Lloyd Smith said, "I think they're going to send a strong signal to Washington D.C that Obamacare and the healthcare plan passed by the liberals in Washington is not what they want here in Missouri".

David Dillon with the Missouri Hospital Association said, "Whether this is a national referendum on health insurance and healthcare, I can't tell you, but I can tell you this, that there is a very good chance it will go to the courts and the courts are--most experts say there is a very little chance that a state law would ever trump a federal law."

Political analysts say its passage could send an ominous political message to democrats seeking to hang on to their congressional majority in this year's elections.

If Prop C passes he said it will likely end up in court where federal laws historically trump state laws. Supporters have raised about $75,000 to run radio ads.

They're running during certain conservative talk shows and on christian radio stations.

Opponents have been less centrally organized.